MyBioSource.com's Rat Anti-ORC2 [3G6] is a Rat monoclonal antibody. The Rat Anti-ORC2 [3G6] Antibody was generated using ORC2, and ORC2L as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Immunoprecipitation, and Western Blot.
Description
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins ORC2L is a subunit of the ORC complex ORC2L forms a core complex with ORC3L 4L and 5L It also interacts with CDC45L and MCM10 which are proteins known to be important for the initiation of DNA replication ORC2L specifically associate with the origin of replication of Epstein Barr virus in human cells and is thought to be required for DNA replication from viral origin of replication